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First human SMUG1 structures reveal how cells repair DNA

Researchers have captured the first atomic structures of human SMUG1, an enzyme that helps cells repair damaged DNA. The findings...

Positive results from kidney transplantation study

Hansa Biopharma AB has announced positive topline results from the European 20-HMedIdeS-19 Post Authorization Efficacy Study (PAES), an open-label...

New Tourette syndrome drug shows promise in phase III trial

Continued use of a drug called ecopipam can cut the risk of relapse in half for children battling tics...

Collaboration to advance clinical trial platform for colorectal cancer

The Colorectal Cancer Alliance and the Global Coalition for Adaptive Research (GCAR) have announced a strategic collaboration to establish...

New peptides slip into cells to block hard-to-target proteins

Many diseases are driven by proteins interacting with each other inside cells. But blocking these interactions with drugs is...

Lung cancer cells switch identity to resist treatment

Cancer scientists have discovered that lung cancer cells can change their identity to resist treatment. Research published in Molecular Oncology...

Could anaemia drug have potential as cancer treatment?

Common medications used to treat anaemia may also slow down cancer cell growth, according to new research from Finland. Researchers...

Base to Base biotech podcast 61: Making tumours visible, and taking on tough challenges

This week, we speak with John Friend, CEO of Kazia Therapeutics; and have a conversation with PureTech Health CEO...

Paediatric pneumococcal vaccine programme advancing

Pfizer Inc. has announced data from its phase 2 study evaluating the safety, tolerability and immunogenicity of a four-dose...

FDA clearance for universal dual-target CAR-T candidate

Qihan Biotech’s QT-019C has received Investigational New Drug (IND) clearance from the U.S. Food and Drug Administration (FDA). QT-019C is...

Positive data from chronic scrotal content pain trial

Sustained Therapeutics, Inc. has presented additional data from its phase 2 study evaluating ST-01, a proprietary non-opioid sustained-release small...

Thalassaemia treatment gets EU approval

Agios Pharmaceuticals, Inc. has revealed that the European Commission has granted marketing authorisation for PYRUKYND (mitapivat), an oral pyruvate...

New data from Parkinson’s disease trial

TreeFrog Therapeutics is presenting new preclinical data on TFG-001 at the 7th World Parkinson’s Conference. TFG-001, a 3D neural microtissue...

Restoring the “longevity protein”

AvaĂ­ Bio, Inc., an emerging biotechnology company developing cell-based therapies for diabetes, age-related disorders, and anti-aging, has announced -...

Positive topline results from phase 2 recurrent ovarian cancer trial

OSE Immunotherapeutics SA has announced the release of the abstract selected for an oral presentation at the upcoming ASCO...

Rare oral cancer has distinct genetic profile

Cancer diagnosis can be challenging, and delayed diagnosis can allow cancer to progress, complicating treatment. Oral squamous cell carcinoma (OSCC),...

New tool decodes structures and motifs of RNA

Modern biology now looks deeper into the cells of living organisms than ever before. Researchers from the chairs of...

Elite immune cells lead fight against multiple myeloma

Immunotherapy for cancer works like a guided missile, directing the body’s immune cells toward tumour cells. However, not all...

National framework to strengthen UK advanced therapy clinical trials

A new framework designed to support the standardisation and expansion of advanced therapy clinical trials has launched in the...

Sensor detects Alzheimer’s and Parkinson’s in blood

For the first time, therapeutically effective medications are now available for Alzheimer’s disease. Effective symptomatic therapies also exist for...

Base to Base biotech podcast 60: Delivery method reduces prostate cancer tumour size

This week, we have a conversation with the founder, director and chief scientific advisor of Alessa Therapeutics, Pamela Munster. Base...