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Data show unresectable patients becoming eligible for surgery

Jim Cornall -
Brenus Pharma has announced first data from the phase Ia dose escalation of BreAK CRC-001. Nine unresectable patients were...

Personalised cancer vaccine with immunotherapy reduces melanoma recurrence after surgery

Jim Cornall -
Adding a personalised mRNA-based cancer vaccine to immunotherapy after surgery for high-risk melanoma reduced the risk of recurrence or...

AI drug choices may cost millions

Jim Cornall -
Large language models (LLMs), such as ChatGPT and Claude, are increasingly being used to provide health information to the...

Researchers reprogramme pancreatic cancer tumour microenvironment

Jim Cornall -
Pancreatic cancer is one of the most aggressive and difficult-to-treat cancers. One reason for its resistance to therapy is...

Base to Base biotech podcast 81: Breakthrough in shrinking tumours and restoring mitochondrial metabolism to address obesity

Jim Cornall -
This week, we talk about mitochondria and obesity with Jon Rees, co-founder and CEO of MitoRx Therapeutics, and also...

New bacteria discovered in DNA samples from prostate cancer patients

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University of East Anglia researchers have discovered the genetic blueprints of 18 new bacterial species collected from prostate cancer...

Estuary Biotherapeutics launches with $103m to develop gene therapies for kidney disease

Jim Cornall -
Estuary Biotherapeutics, Inc. has launched with $103m in total committed financing. The financing will support advancement of the company’s two...

Data show reduction in skin epigenetic age and systemic inflammatory biomarkers

Jim Cornall -
Rubedo Life Sciences has revealed new phase 1b clinical findings for RLS-1496, its lead investigational GPX4 modulator. In patients with...

Blood proteins may offer clues to gut health in coeliac disease

Jim Cornall -
Coeliac disease is an autoimmune condition in which the immune system reacts adversely to gluten. Eating gluten causes inflammation...

IMU and UK Biobank to generate world’s most detailed picture of the human immune system

Jim Cornall -
IMU Biosciences has announced a collaboration with UK Biobank to generate large-scale multi-omic immune profiling data from 80,000 blood...

Positive results from schizophrenia study

Jim Cornall -
Tortugas Neuroscience has announced positive phase 2b trial results for obuprazine (TRTL-107), the company’s investigational treatment for schizophrenia. Results from...

Jyong Biotech looks to Texas

Jim Cornall -
Jyong Biotech Ltd. says it plans to establish a potential new manufacturing facility and US operations centre in Texas. The...

New AI tool helps diagnose Ewing sarcoma

Jim Cornall -
A team from the Universitat Politècnica de València (UPV) and the University of Valencia (UV) has developed and validated...

Antibody shows attacking tumour environment also kills cancer cells

Jim Cornall -
Basque biopharmaceutical company Oncomatryx has taken part, together with German research institutions, in a study showing in patient tumour...

FDA clearance leads to influenza trial

Jim Cornall -
Shanghai Ark Biopharmaceutical Co., Ltd. (ArkBio) has announced that the U.S. Food and Drug Administration (FDA) has granted its...

Plasmonic coating paves way for rapid sepsis diagnosis

Jim Cornall -
A research team has developed a label-free surface-enhanced Raman scattering (SERS) analysis technology that rapidly detects extremely low concentrations...

Mentara Therapeutics launches to tackle dyskinesia

Jim Cornall -
Mentara Therapeutics, a new neuropsychiatry company backed by SPRIM Global Investments, has launched with the acquisition of EM-221, now...

Base to Base biotech podcast 80: Targeting tumour acidity, and developing allosteric therapies

Jim Cornall -
This week, we chat with Ryan Beal, a cancer survivor and founder and CEO of Dyve Biosciences, about tumour...

IQVIA looks to help life sciences companies predict clinical trial outcomes

Jim Cornall -
IQVIA has launched IQVIA Life Science Models to help predict clinical trial outcomes. IQVIA Life Science Models are a suite...

New regulator of muscle regeneration discovered

Jim Cornall -
Skeletal muscles can regenerate following an injury, a process depending on muscle stem cells. In healthy resting muscle, these...

AI system could transform global rabies testing

Jim Cornall -
Rabies virus detection in cell cultures could soon become faster and more accessible, thanks to a world-first AI system...