DairyX Foods Ltd. In Israel has announced a major advancement in creating authentic milk proteins without cows, using precision fermentation.
The foodtech start-up has developed a method to produce casein proteins that can self-assemble into micelles. Micelles are the primary building blocks of dairy products, such as cheese and yogurt.
DairyX has also refined a complementary technology to enhance the gelation of its casein micelles, considered the ‘holy grail’ of the industry. DairyX’s gelating micelles enable manufacturers to produce firm, stretchy and creamy products using their existing dairy-making processes.
‘Smarter’ casein with precision fermentation
Casein micelles are key to the appealing sensory profile of dairy products. DairyX’s precision fermentation technology uses microorganisms (specifically yeast) to produce smart casein proteins.
“Not all caseins produced using precision fermentation are alike,” said Maya Bar-Zeev, head of product development and downstream processing.
“We trained yeast to produce the next generation of casein. DairyX’s patent-pending casein is an advanced form created to precisely and effectively organize into micelles.”
“The industry knows quite well that caseins are extremely hard to produce using precision fermentation, so our initial goal was to solve this problem. Once we successfully crafted caseins, the next major challenge was to upgrade caseins so they could self-assemble into gelating micelles to produce the dairy properties manufacturers are seeking,” said DairyX CEO and founder Arik Ryvkin.
Currently, manufacturers of animal-free dairy products use additives, like stabilizers, emulsifiers and thickeners, which don’t perform as well as cow’s milk and can add unpleasant aftertastes.
“DairyX caseins have amino acid sequences identical to those of their animal counterparts, making them, in fact, non-genetically modified,” said Galit Kuznets, head of strain development and fermentation.
“Our casein also eliminates the need for hormones and antibiotics applied in dairy farms.”
Maximised efficiency
For consumers, taste and price are dairy’s two most important features. DairyX addresses taste with its caseins while also making non-animal dairy affordable. The company is creating yeast strains that produce exceptionally high casein yields in short timeframes. This approach ensures that DairyX’s ingredients are cost-effective – crucial for adoption by dairy manufacturers.
“Another significant challenge that dairy companies face is adapting their production facilities to use new ingredients,” Bar-Zeev said.
“This is why we created a drop-in replacement for milk that does not require process changes or retooling.”
The future of dairy proteins
Ryvkin said: “To genuinely mimic traditional dairy, producers needed to start with different source ingredients.”
Worldwide, 270 million cows spend their lives in the production of dairy products. DairyX said it is devoted to lowering the dairy industry’s dependence on traditional milk as a raw ingredient. Doing so promotes sustainability, improved animal welfare, and the use of land and water for better causes.
As protein ingredients, DairyX micelles have no cholesterol or lactose, the company added.
DairyX deep tech
Kuznets noted: “We have achieved several key objectives with our solutions. Our biological design genetically manipulated yeast to produce functional caseins that we organized into micelles. We developed a fast-tracked screening process that simulated evolution to locate super-producers of protein from among millions of yeast strains. Our machine-learning models simulated fermentation to determine optimal fermentation conditions. We have proven our ability to create a gel from reconstituted casein micelles. All these ingenuities have helped us work smarter and faster to create highly functional micelles.”
“Recreating casein protein micelles from yeast is an important milestone,” Ryvkin concluded.
“We are currently focused on scaling up our fermentation process and collaborating with dairy companies.”
Jim Cornall is editor of Deeptech Digest and publisher at Ayr Coastal Media. He is an award-winning writer, editor, photographer, broadcaster, designer and author. Contact Jim here.
