Cerebrovascular disease can lead to serious aftereffects if treatment is delayed, but it is difficult to detect before symptoms appear. KAIST researchers have developed an AI technology that analyses real-life daily activity and environmental data from older adults to identify digital behavioural markers of cerebrovascular disease risk based on subtle changes at home.
A research team led by Lisa Lim from KAIST’s Department of Civil and Environmental Engineering, in collaboration with Jo Woon Chong from the School of Electronic and Electrical Engineering at Sungkyunkwan University and Kyung-Hee Cho from the Department of Neurology at Korea University Anam Hospital, has developed an AI framework that uses long-term data collected in the homes of older adults to identify the prodromal phase of cerebrovascular disease and assess imminent diagnostic risk.
The study was based on lifelog data from 1,224 older adults collected by LivOn Care Co., Ltd. in real residential environments. The research team analysed 13,362 two-week lifelog samples, demonstrating the possibility of detecting early warning signs through subtle changes in daily life, rather than relying only on the conventional approach of treating the disease after it has already occurred.
The research team developed AI technology that identifies cerebrovascular disease risk stages by analysing daily activity, sleep, circadian rhythm, and indoor environmental information, together with age and chronic disease data. This shows that changes in everyday living patterns, which are difficult to capture through hospital examinations alone, can serve as important clues for detecting early risk signals of cerebrovascular disease.
The team also succeeded in assessing whether a cerebrovascular disease diagnosis was approaching by analysing changes in lifestyle patterns over time. When lifelog data from within four weeks before diagnosis were classified as the “imminent diagnostic risk period” and data from 12 weeks before diagnosis were classified as the “non-imminent period,” the AI distinguished between the two periods with a high accuracy of 96.53%. This result suggests that even before a hospital visit, small changes in daily life may help identify whether the risk of cerebrovascular disease has increased.
Another feature of this study is that the AI does not simply determine whether a risk exist, but also applies explainable AI to identify the lifestyle patterns and environmental factors behind its judgement.
The analysis showed that older adults in the prodromal phase of cerebrovascular disease tended to show frequent continuous activity between 10 p.m. and 2 a.m., a time when the body would normally be preparing for sleep. In other words, irregular daily rhythms, such as delayed sleep onset and a reduced distinction between day and night activity, were closely associated with prodromal signals of cerebrovascular disease.
The researchers also found that as the time of diagnosis approached, the frequency of continuous activity during the evening period from 6 p.m. to 10 p.m. noticeably decreased, while inactive time increased. Low indoor humidity, indicating a dry indoor environment, also emerged as an important factor in identifying an imminent diagnostic risk.
The research team expects this technology to be used as a digital healthcare tool that can objectively monitor the health status of older adults who may have difficulty clearly describing their own condition, while providing useful early warning indicators to medical professionals and caregivers.
However, the team explained that this study does not predict the exact onset of cerebrovascular disease or replace clinical diagnosis. Rather, it is a supportive technology intended to aid prevention and early medical consultation, and prospective validation in larger patient groups will be necessary before actual clinical application.
Lim said: “The key point of this study is not that AI should replace a hospital diagnosis, but that it can first detect risk signals in small lifestyle changes at home and help connect patients to medical care at the right time,” adding, “We expect this technology to contribute to a shift from a healthcare system that treats disease after it occurs to one that supports prevention and early intervention.”
The study was published in npj Digital Medicine.